Hydrogen sulfide: a gaseous signaling molecule modulates tissue homeostasis: implications in ophthalmic diseases

Hydrogen sulfide: a novel gaseous signaling molecule and intracellular Ca2+ regulator in rat parotid acinar cells.

In addition to nitric oxide (NO), hydrogen sulfide (H2S) is recognized as a crucial gaseous messenger that exerts many biological actions in various tissues. An attempt was made to assess the roles and underlying mechanisms of both gases in isolated rat parotid acinar cells. Ductal cells and some acinar cells were found to express NO and H2S synthases. Cevimeline, a muscarinic receptor agonist ...

Hydrogen sulfide: a novel gaseous signaling molecule and intracellular Ca regulator in rat parotid acinar cells

Moustafa A, Habara Y. Hydrogen sulfide: a novel gaseous signaling molecule and intracellular Ca regulator in rat parotid acinar cells. Am J Physiol Cell Physiol 309: C480–C490, 2015. First published July 29, 2015; doi:10.1152/ajpcell.00147.2015.—In addition to nitric oxide (NO), hydrogen sulfide (H2S) is recognized as a crucial gaseous messenger that exerts many biological actions in various ti...

A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide.

Emergence of hydrogen sulfide as an endogenous gaseous signaling molecule in cardiovascular disease.

Long recognized as a malodorous and highly toxic gas, recent experimental studies have revealed that hydrogen sulfide (H2S) is produced enzymatically in all mammalian species including man and exerts several critical actions to promote cardiovascular homeostasis and health. During the past 15 years, scientists have determined that H2S is produced by 3 endogenous enzymes and exerts powerful effe...

Hydrogen sulfide : a novel gaseous signaling molecule and intracellular Ca 2 + regulator in 1 rat parotid acinar cells

Hydrogen sulfide: a novel gaseous signaling molecule and intracellular Ca regulator in 1 rat parotid acinar cells 2 3 Amira Moustafa1,2 and Yoshiaki Habara1 4 Laboratory of Physiology, Department of Biomedical Sciences, Graduate School of 5 Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan; Department of 6 Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 4...